Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970478 | 0.95 | LCK (0.41) | LCK | |
| SCHEMBL7982214 | 0.87 | ALDH1A1 (0.40) | LCKCCNT1 | |
| SCHEMBL7969619 | 0.86 | LCK (0.37) | LCKCCNT1 | |
| SCHEMBL7983242 | 0.85 | LCK (0.42) | LCK | |
| SCHEMBL7983065 | 0.85 | LCK (0.52) | LCK | |
| SCHEMBL7983561 | 0.82 | LCK (0.47) | LCK | |
| SCHEMBL7980193 | 0.82 | LCK (0.39) | LCK | |
| SCHEMBL7984051 | 0.81 | LCK (0.45) | LCK | |
| SCHEMBL7979958 | 0.81 | LCK (0.56) | LCK | |
| SCHEMBL7983674 | 0.79 | ALDH1A1 (0.41) | LCKCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | claimed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |