Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969927 | 1.00 | PLA2G4A (0.57) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7970621 | 1.00 | PLA2G4A (0.57) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7209884 | 1.00 | PLA2G4A (0.57) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7969907 | 1.00 | PLA2G4A (0.57) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7209788 | 1.00 | PLA2G4A (0.57) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7969916 | 1.00 | PLA2G4A (0.57) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7970622 | 1.00 | PLA2G4A (0.57) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7956711 | 0.99 | POLB (0.56) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7956707 | 0.99 | POLB (0.56) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1481794 | 0.96 | POLB (0.59) | PLA2G4APOLBKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |