Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.70 |
| ▸ | CTSL | P07711 | 3/20 | 0.65 |
| ▸ | CTSB | P07858 | 2/20 | 0.65 |
| ▸ | CTSS | P25774 | 1/20 | 0.65 |
| ▸ | CTSK | P43235 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | KDM1A | O60341 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.57 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970037 | 0.91 | HDAC8 (0.65) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7370634 | 0.88 | HDAC8 (0.73) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL15627733 | 0.86 | CTSL (0.72) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL805151 | 0.86 | CTSL (0.72) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL4655258 | 0.86 | TACR1 (0.78) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL8114770 | 0.84 | HDAC3 (0.69) | TACR1CTSSCTSKHDAC8HDAC3 | |
| SCHEMBL10049956 | 0.83 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL8668091 | 0.83 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL12052836 | 0.83 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL16095807 | 0.83 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| CN-1260345-A | Hydrazide compound, its preparing method and medicine compositions thereof | ADIR ET COMPANGIE (FR) | 2000-07-19 | — | — | CN | disclosed |