Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983539 | 0.77 | LCK (0.53) | POLBLCKALDH1A1MAPTHTT | |
| SCHEMBL25318990 | 0.70 | POLB (0.46) | POLBMAOBALDH1A1MAPTHTT | |
| SCHEMBL21676385 | 0.69 | SYK (0.55) | POLBMAOBALDH1A1KDM4ERCE1 | |
| SCHEMBL31026839 | 0.69 | TP53 (0.35) | — | |
| SCHEMBL25429303 | 0.68 | POLB (0.46) | POLBMAOBALDH1A1MAPTHTT | |
| SCHEMBL15748775 | 0.67 | POLB (0.57) | POLBMAOBALDH1A1MAPTHTT | |
| SCHEMBL30508860 | 0.67 | POLB (0.53) | POLBMAOBALDH1A1MAPTHTT | |
| SCHEMBL31353079 | 0.66 | GRIN2D (0.36) | LCKALDH1A1MAPTHTTKDM4E | |
| SCHEMBL20532682 | 0.66 | POLB (0.52) | POLBMAOBALDH1A1MAPTHTT | |
| SCHEMBL31026868 | 0.66 | GRIA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |