Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970069 | 0.77 | POLB (0.41) | LCKTSHRALDH1A1MAPTHTT | |
| SCHEMBL7984386 | 0.74 | LCK (0.47) | LCK | |
| SCHEMBL7983392 | 0.74 | LCK (0.52) | LCKALDH1A1MAPTHTTPOLB | |
| SCHEMBL7983711 | 0.72 | LCK (0.94) | LCKSRC | |
| SCHEMBL21642597 | 0.70 | KDR (0.56) | LCKTSHRPOLBHTR2CSRC | |
| SCHEMBL17310080 | 0.70 | ALDH1A1 (0.55) | TSHRALDH1A1MAPTHTTPOLB | |
| SCHEMBL7980325 | 0.70 | LCK (1.00) | LCK | |
| SCHEMBL7970375 | 0.70 | LCK (0.89) | LCKSRC | |
| SCHEMBL7987001 | 0.70 | LCK (1.00) | LCK | |
| SCHEMBL7979668 | 0.69 | LCK (0.75) | LCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |