Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957078 | 1.00 | CTSD (0.54) | CTSDBACE1 | |
| SCHEMBL7957558 | 0.92 | BACE1 (0.54) | CTSDBACE1 | |
| SCHEMBL7961830 | 0.92 | BACE1 (0.54) | CTSDBACE1 | |
| SCHEMBL7963620 | 0.92 | BACE1 (0.54) | CTSDBACE1 | |
| SCHEMBL7957041 | 0.90 | CTSD (0.54) | CTSDBACE1 | |
| SCHEMBL12247172 | 0.90 | CTSD (0.50) | CTSDBACE1 | |
| SCHEMBL7948278 | 0.90 | BACE1 (0.50) | CTSDBACE1 | |
| SCHEMBL7957950 | 0.90 | BACE1 (0.50) | CTSDBACE1 | |
| SCHEMBL7956240 | 0.90 | BACE1 (0.50) | CTSDBACE1 | |
| SCHEMBL7957894 | 0.90 | CTSD (0.54) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |