Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 2/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966686 | 0.92 | EBP (0.36) | EBPSIGMAR1BCHEPGRHSD11B1 | |
| SCHEMBL7971511 | 0.90 | EBP (0.38) | EBPSIGMAR1BCHEUBE2MDCUN1D1 | |
| SCHEMBL7967723 | 0.90 | BCHE (0.43) | EBPSIGMAR1BCHEUBE2MDCUN1D1 | |
| SCHEMBL7958064 | 0.88 | EBP (0.38) | EBPSIGMAR1BCHEUBE2MDCUN1D1 | |
| SCHEMBL7957575 | 0.88 | EBP (0.38) | EBPSIGMAR1BCHE | |
| SCHEMBL7972427 | 0.86 | SIGMAR1 (0.39) | EBPSIGMAR1PGRHSD11B1TSHR | |
| SCHEMBL7957763 | 0.86 | EBP (0.36) | EBPSIGMAR1BCHEUBE2MDCUN1D1 | |
| SCHEMBL7970875 | 0.86 | SIGMAR1 (0.44) | EBPSIGMAR1BCHEUBE2MDCUN1D1 | |
| SCHEMBL7971788 | 0.85 | EBP (0.36) | EBPSIGMAR1PGRHSD11B1 | |
| SCHEMBL7970685 | 0.85 | SIGMAR1 (0.40) | EBPSIGMAR1BCHEUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265439-B1 | Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives | G.D. SEARLE & CO. | 2001-07-24 | — | — | US | disclosed |
| US-5451604-A | Useful in organ transplant surgery | G. D. SEARLE & CO. (US) | 1995-09-19 | — | — | US | disclosed |