SCHEMBL797018

SCHEMBL797018

C=C(C)OC(=O)CCNC(=O)Nc1nccs1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.61
ALOX15 P16050 1/20 0.47
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 2/20 0.45
PKM P14618 1/20 0.45
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
ACP1 P24666 1/20 0.44
AURKA O14965 1/20 0.43
PIM1 P11309 1/20 0.43
CDK2 P24941 1/20 0.43
GSK3B P49841 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
HTT P42858 2/20 0.42
NPC1 O15118 1/20 0.42
PPARG P37231 1/20 0.42
RAB9A P51151 1/20 0.42
NCOR2 Q9Y618 1/20 0.42
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12721816 0.81 SMN1; SMN2 (0.66) SMN1; SMN2ALOX15MAPK1ALDH1A1PKM
SCHEMBL797016 0.79 HTT (0.43) SMN1; SMN2ALDH1A1LMNATSHRHTT
SCHEMBL13336537 0.78 SMN1; SMN2 (0.62) SMN1; SMN2ALOX15MAPK1ALDH1A1PKM
SCHEMBL208500 0.77 L3MBTL1 (0.55) SMN1; SMN2ALOX15MAPK1ALDH1A1PKM
SCHEMBL796374 0.73 PRSS1 (0.32) LMNA
SCHEMBL3430425 0.73 SMN1; SMN2 (0.77) SMN1; SMN2ALOX15MAPK1ALDH1A1PKM
Hydrochloric Acid SCHEMBL17186179 0.72 SMN1; SMN2 (0.74) SMN1; SMN2ALOX15MAPK1ALDH1A1PKM
SCHEMBL13411177 0.71 SMN1; SMN2 (0.67) SMN1; SMN2ALOX15MAPK1ALDH1A1PKM
SCHEMBL13336615 0.71 SMN1; SMN2 (0.62) SMN1; SMN2ALOX15MAPK1ALDH1A1PKM
SCHEMBL17146214 0.71 POLB (0.55) SMN1; SMN2MAPK1LMNATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8728687-B2 Resin, pigment dispersion, colored curable composition, color filter produced using the same, and method for producing the same FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-20120067236-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND RELIEF PRINTING PLATE AND PROCESS FOR MAKING SAME FUJIFILM CORPORATION (JP) 2012-03-22 US disclosed
US-7927772-B2 Pigment, a dispersant, a solvent, a polymerizable compound, a photopolymerization initiator; solvents having different boiling temperatures, improving dispersion stability, film thickness uniformity, smooth pattern without any irregularities, without any residue when exposing and developing. FUJIFILM CORPORATION (JP) 2011-04-19 US disclosed
US-20110003241-A1 RESIN, PIGMENT DISPERSION, COLORED CURABLE COMPOSITION, COLOR FILTER PRODUCED USING THE SAME, AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2011-01-06 US disclosed
US-20080268354-A1 COLORED PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER USING THE SAME AND METHOD OF PRODUCING COLOR FILTER FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed