Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757803 | 1.00 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL7970364 | 1.00 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL5758612 | 1.00 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL5758608 | 1.00 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL7096369 | 0.99 | HTR2C (0.48) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL18618469 | 0.86 | KDM1A (0.44) | HTR2CPLGMEN1KMT2APOLB | |
| SCHEMBL7119720 | 0.84 | HTR2C (0.68) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL7119723 | 0.84 | HTR2C (0.68) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL7119711 | 0.84 | HTR2C (0.68) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL5090671 | 0.83 | SLC6A4 (0.46) | SLC6A2SLC6A4SLC6A3HTR2CPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303627-B1 | FOR THERAPY OF PHYSIOLOGICAL AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY | 2001-10-16 | — | — | US | disclosed |
| WO-1999065487-A1 | INHIBITORS OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0965587-A1 | Tetrahydropyridinyl- and piperidinyl Inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |