Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | F11 | P03951 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.38 |
| ▸ | ATR | Q13535 | 3/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972241 | 0.89 | F9 (0.41) | F9F10F11F7BRD4 | |
| SCHEMBL7975112 | 0.83 | F9 (0.47) | F9F10F11F7BRD4 | |
| SCHEMBL7970443 | 0.83 | ATR (0.39) | F9F10F11BRD4CHEK2 | |
| SCHEMBL7971003 | 0.80 | F9 (0.43) | F9F10F11F7CHEK2 | |
| SCHEMBL10172686 | 0.76 | CHEK2 (0.69) | F9F10F11F7CHEK2 | |
| SCHEMBL20307729 | 0.75 | F9 (0.40) | F9F10F11F7CHEK2 | |
| SCHEMBL7977818 | 0.74 | F9 (0.48) | F9F10F11F7 | |
| SCHEMBL10172741 | 0.73 | F9 (0.53) | F9F10F11F7CHEK2 | |
| SCHEMBL16258933 | 0.73 | F9 (0.47) | F9F10F11F7CHEK2 | |
| SCHEMBL16258970 | 0.73 | F9 (0.48) | F9F10F11F7CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |