Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | F11 | P03951 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975112 | 0.90 | F9 (0.47) | F9F10F11F7NPBWR1 | |
| SCHEMBL7969289 | 0.85 | F9 (0.48) | F9F10F11F7GUSB | |
| SCHEMBL16258933 | 0.83 | F9 (0.47) | F9F10F11F7MAPK14 | |
| SCHEMBL7962296 | 0.82 | NPBWR1 (0.36) | MAPK14CSNK1DCSNK1EJAK2CDK4 | |
| SCHEMBL20307729 | 0.81 | F9 (0.40) | F9F10F11F7CDK4 | |
| SCHEMBL7969287 | 0.81 | F9 (0.46) | F9F10F11F7NPBWR1 | |
| SCHEMBL7973518 | 0.81 | F9 (0.43) | F9F10F11F7JAK2 | |
| SCHEMBL7973330 | 0.79 | F9 (0.44) | F9F10F11F7CNR1 | |
| SCHEMBL7972949 | 0.78 | F9 (0.46) | F9F10F11F7DHODH | |
| SCHEMBL7960905 | 0.78 | F9 (0.46) | F9F10F11F7DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |