Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 4/20 | 0.49 |
| ▸ | NOS3 | P29474 | 6/20 | 0.46 |
| ▸ | NOS1 | P29475 | 6/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | BLK | P51451 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564022 | 0.94 | QRFPR (0.51) | QRFPRNOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL7569078 | 0.93 | QRFPR (0.50) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL7973909 | 0.89 | QRFPR (0.53) | QRFPRNOS3NOS1CHUKDAPK3 | |
| SCHEMBL7973912 | 0.89 | QRFPR (0.49) | QRFPRNOS3NOS1CHUKDAPK3 | |
| SCHEMBL7972156 | 0.88 | NOS1 (0.47) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL7973735 | 0.87 | QRFPR (0.45) | QRFPRNOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL7973933 | 0.87 | QRFPR (0.50) | QRFPRNOS3NOS1CHUKDAPK3 | |
| SCHEMBL7564087 | 0.85 | QRFPR (0.66) | QRFPRNOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL7563787 | 0.84 | QRFPR (0.64) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL7565050 | 0.82 | QRFPR (0.50) | QRFPRNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046170-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | claimed |