Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 18/20 | 0.65 |
| ▸ | CTRC | Q99895 | 11/20 | 0.65 |
| ▸ | CTSG | P08311 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555873 | 0.88 | CTRC (0.81) | CMA1CTRC | |
| SCHEMBL7959340 | 0.84 | ELANE (0.56) | CMA1CTRC | |
| SCHEMBL5728755 | 0.82 | CMA1 (0.74) | CMA1CTRC | |
| SCHEMBL5728762 | 0.82 | CMA1 (0.74) | CMA1CTRC | |
| SCHEMBL6558220 | 0.81 | CTRC (0.91) | CMA1CTRCCTSG | |
| SCHEMBL7965289 | 0.79 | CTRC (0.73) | CMA1CTRC | |
| SCHEMBL8404958 | 0.79 | CTRC (0.90) | CMA1CTRC | |
| SCHEMBL6556475 | 0.79 | CTRC (1.00) | CMA1CTRC | |
| Hydrochloric Acid SCHEMBL5728984 | 0.78 | CMA1 (0.68) | CMA1CTRCCTSG | |
| Hydrochloric Acid SCHEMBL5728980 | 0.78 | CMA1 (0.68) | CMA1CTRCCTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271238-B1 | USEFUL IN TREATING AND PREVENTING DISEASES INVOLVING CHYMOTRYPSIN TYPE PROTEASES WHICH ARE RELATED TO ASTHMA, ALLERGY, INFLAMMATIONS, RHEUMATISM, HYPERTENSION, HEART FAILURE, MYOCARDIAL INFARCTION, AND CARDIAC HYPERTROPHY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | claimed |