SCHEMBL7970601

SCHEMBL7970601

N=C(N)NC(=N)NCCc1cc(F)ccc1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.39
MAPK8 P45983 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SNCA P37840 1/20 0.34
MTNR1A P48039 2/20 0.34
MTNR1B P49286 2/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ATM Q13315 1/20 0.33
DPP4 P27487 1/20 0.33
CNR1 P21554 1/20 0.32
MPO P05164 1/20 0.32
SPR P35270 1/20 0.31
PLA2G1B P04054 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18624764 0.83 NR3C2 (0.42) NOTUMKMT2AALDH1A1SMN1; SMN2MTNR1A
SCHEMBL17198837 0.82 TAAR1 (0.49) MEN1KMT2AALDH1A1MTNR1ANPC1
SCHEMBL17198796 0.78 HPGD (0.46) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL20258597 0.78 NOTUM (0.70) NOTUMKMT2AMTNR1AMTNR1BMPO
SCHEMBL20258543 0.78 NOTUM (0.56) NOTUMMTNR1AMTNR1BNPC1RAB9A
SCHEMBL17198939 0.78 ST14 (0.38) MAPK8MEN1KMT2ADPP4PLA2G1B
SCHEMBL17198857 0.77 TAAR1 (0.51) ALDH1A1LMNACNR1MAPT
Hydrochloric Acid SCHEMBL30496748 0.77 ST14 (0.37) MAPK8MEN1KMT2ADPP4PLA2G1B
SCHEMBL21562514 0.76 CDK2 (0.46) NOTUMMEN1KMT2ALMNASMN1; SMN2
SCHEMBL21562551 0.76 MTNR1A (0.46) NOTUMMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001010849-A2 SUBSTITUTED ARYLALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-02-15 WO disclosed