SCHEMBL7970671

SCHEMBL7970671

N#CCC(Cl)(Cl)C1CCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080934 0.74 NOS2 (0.30)
SCHEMBL9099720 0.69
SCHEMBL7964712 0.69
SCHEMBL18662530 0.69
SCHEMBL8071773 0.66 EPHX1 (0.39)
SCHEMBL4716389 0.65
SCHEMBL8573723 0.63
Alcohol SCHEMBL8142064 0.62 EPHX1 (0.36)
SCHEMBL24286043 0.60
SCHEMBL15809089 0.60 NOS2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110526864-A New compound, its synthesis and application thereof SPHAERA PHARMA PRIVATE LTD 2019-12-03 CN disclosed
WO-2001002364-A1 NEW NPY ANTAGONISTS ASTRAZENECA AB (SE) 2001-01-11 WO disclosed
US-6043270-A ANTIINFLAMMATORY AGENTS PROCYON PHARMACEUTICALS, INC. (US) 2000-03-28 US disclosed
US-5962498-A Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity PROCYON PHARMACEUTICALS, INC. (US) 1999-10-05 US disclosed
US-5955501-A DERIVED FROM PHORBOIDS OF THE DITERPENE- AND BENZOLACTAM-CLASSES. PROCYON PHARMACEUTICALS, INC. (US) 1999-09-21 US disclosed
US-5891870-A ANTIINFLAMMATORY AGENTS USING BENZODITERPENES AND BENZOLACTAMS PROCYON PHARMACEUTICALS, INC. (US) 1999-04-06 US disclosed
US-5891906-A Polyacetate-derived phorboids having anti-inflammatory and other uses PROCYON PHARMACEUTICALS, INC. (US) 1999-04-06 US disclosed
US-5886019-A REPLACEMENT OF HYDROXYMETHYL OR-ETHYL GROUP ON TRICYCLIC AROMATIC HETEROCYCLIC COMPOUNDS HAVING INDOLE, INDENE, BENZOFURAN OR BENZOTHIOPHENE SKELETON; ANTIINFLAMMATORY, ANTIVIRAL PROCYON PHARMACEUTICALS, INC. (US) 1999-03-23 US disclosed
US-5750568-A DITERPENE PHORBOIDS PROCYON PHARMACEUTICALS, INC. (US) 1998-05-12 US disclosed
US-5716968-A ANTIINFLAMMATORY AGENTS; VIRICIDE PROCYON PHARMACEUTICALS, INC. (US) 1998-02-10 US disclosed
EP-0455271-B1 Anti-inflammatory compositions PROCYON PHARM INC (US) 1997-08-20 EP disclosed
US-5643948-A ANTIINFLAMMATORY, ANTICANCER PROCYON PHARMACEUTICALS, INC. (US) 1997-07-01 US disclosed
US-5145842-A Protein kinase c. modulators. d. ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) 1992-09-08 US disclosed
EP-0455271-A2 Anti-inflammatory compositions PROCYON PHARMACEUTICALS, INC. (US) 1991-11-06 EP disclosed