Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7970741

CCCCCN1CC[N+](CCCCC)=C1F.O=C([O-])C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 9/20 0.41
EEF2K O00418 1/20 0.36
FAAH O00519 8/20 0.32
TACR1 P25103 1/20 0.32
CES1 P23141 5/20 0.31
CES2 O00748 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7967266 0.99 CCR5 (0.43) CCR5EEF2KFAAHTACR1CES1
Trifluoroacetic Acid SCHEMBL7973674 0.93 CCR5 (0.37) CCR5EEF2K
Iodide SCHEMBL7246570 0.86 EEF2K (0.46) EEF2KFAAHMEN1KMT2A
Bromide SCHEMBL4651688 0.86 EEF2K (0.43) EEF2KFAAHMEN1KMT2A
Hydrochloric Acid SCHEMBL7224338 0.86 EEF2K (0.43) EEF2KFAAHMEN1KMT2A
Trifluoroacetic Acid SCHEMBL7967442 0.85 CCR5 (0.33) CCR5
Bromide SCHEMBL4651633 0.84 EEF2K (0.45) EEF2KFAAHMEN1KMT2A
Hydrochloric Acid SCHEMBL7216909 0.84 EEF2K (0.45) CCR5EEF2KFAAHMEN1KMT2A
Iodide SCHEMBL7216929 0.84 EEF2K (0.48) EEF2KFAAHMEN1KMT2A
Hydrochloric Acid SCHEMBL7224238 0.78 MEN1 (0.39) EEF2KMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6222046-B1 AS TRIFLUOROACETOXYLATION AGENT MITSUI CHEMICALS, INC. (JP) 2001-04-24 US disclosed
EP-0982299-A1 Tetraalkylfluoroformamidinium trifluoroacetate and its use as trifluoroacetoxylation agent Mitsui Chemicals, Inc. (JP) 2000-03-01 EP disclosed