Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.43 |
| ▸ | F9 | P00740 | 3/20 | 0.43 |
| ▸ | F11 | P03951 | 3/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 12/20 | 0.41 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258934 | 0.91 | F10 (0.54) | F10F9F11F7F2 | |
| SCHEMBL7972318 | 0.81 | CHEK2 (0.56) | F10F9F11CHEK2F7 | |
| SCHEMBL20307734 | 0.79 | TOP1 (0.32) | F10F9F11 | |
| SCHEMBL10139933 | 0.78 | CHEK2 (0.67) | CHEK2 | |
| SCHEMBL7975521 | 0.78 | F10 (0.63) | F10F9F11CHEK2F7 | |
| SCHEMBL10139891 | 0.77 | CHEK2 (0.69) | F10F9F11CHEK2 | |
| SCHEMBL7971691 | 0.77 | CHEK2 (0.40) | F10F9F11CHEK2F7 | |
| SCHEMBL10140008 | 0.77 | F10 (0.57) | F10F9F11F7F2 | |
| SCHEMBL10139996 | 0.76 | F10 (0.54) | F10F9F11F7F2 | |
| SCHEMBL10139883 | 0.76 | CHEK2 (0.65) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |