Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351411 | 0.81 | TDP1 (0.34) | ALDH1A1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL22341300 | 0.79 | GRN (0.33) | SLC1A3SLC1A2SLC1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL28035184 | 0.79 | TDP1 (0.36) | ALDH1A1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL4989912 | 0.79 | SLC1A3 (0.36) | ALDH1A1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL7595368 | 0.78 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL96140 | 0.76 | ACE2 (0.32) | SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL9488746 | 0.75 | ACE2 (0.31) | — | |
| SCHEMBL6234057 | 0.75 | CA2 (0.47) | ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL31499508 | 0.75 | ACE2 (0.31) | — | |
| SCHEMBL29105339 | 0.75 | ACE2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187924-B1 | INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TUMOR NECROSIS FACTOR-ALPHA-MEDIATED DISEASES | DARWIN DISCOVERY, LTD. (GB) | 2001-02-13 | — | — | US | disclosed |