Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971163 | 1.00 | OPRD1 (0.58) | OPRD1 | |
| SCHEMBL7958072 | 0.90 | OPRD1 (0.73) | OPRD1 | |
| SCHEMBL7958067 | 0.90 | OPRD1 (0.73) | OPRD1 | |
| SCHEMBL7968835 | 0.84 | OPRD1 (0.81) | OPRD1 | |
| SCHEMBL7968839 | 0.84 | OPRD1 (0.81) | OPRD1 | |
| SCHEMBL5082997 | 0.81 | OPRD1 (0.71) | OPRD1 | |
| SCHEMBL5083008 | 0.81 | OPRD1 (0.71) | OPRD1 | |
| SCHEMBL12016540 | 0.81 | CYP1A2 (0.60) | OPRD1 | |
| SCHEMBL7969266 | 0.80 | — | — | |
| SCHEMBL7968827 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200978-B1 | FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS | PFIZER INC. | 2001-03-13 | — | — | US | disclosed |