Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592877 | 0.80 | ALDH1A1 (0.33) | CDC25BIDO1MAOAMAOBAKT1 | |
| SCHEMBL973342 | 0.72 | CDC25B (0.39) | CDC25BIDO1MAOAMAOBAKT1 | |
| SCHEMBL2585200 | 0.72 | — | — | |
| SCHEMBL4981136 | 0.67 | CDC25B (0.42) | CDC25BIDO1MAOAMAOBAKT1 | |
| SCHEMBL591093 | 0.67 | CDC25B (0.48) | CDC25BIDO1MAOAMAOBAKT1 | |
| SCHEMBL388722 | 0.65 | — | — | |
| SCHEMBL8758921 | 0.63 | GSK3A (0.33) | GSK3AGSK3B | |
| SCHEMBL10316302 | 0.63 | GSK3A (0.33) | GSK3AGSK3B | |
| SCHEMBL5323960 | 0.62 | — | — | |
| SCHEMBL31001022 | 0.59 | CYP1A2 (0.55) | CDC25BIDO1MAOAMAOBAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |