Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.83 |
| ▸ | CTSK | P43235 | 7/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971421 | 0.91 | TACR1 (1.00) | TACR1CTSKALDH1A1CTSLCTSS | |
| SCHEMBL7970040 | 0.90 | TACR1 (0.67) | TACR1CTSKHDAC8F2CTSL | |
| SCHEMBL8118400 | 0.88 | TACR1 (0.61) | TACR1CTSKHDAC8ALDH1A1CTSL | |
| SCHEMBL10706786 | 0.86 | HDAC8 (0.68) | TACR1CTSKHDAC8F2CTSL | |
| SCHEMBL7970037 | 0.86 | HDAC8 (0.65) | TACR1CTSKHDAC8F2ALDH1A1 | |
| SCHEMBL14684392 | 0.85 | HDAC8 (0.64) | TACR1CTSKHDAC8F2CTSL | |
| SCHEMBL7317573 | 0.85 | HDAC8 (0.64) | TACR1CTSKHDAC8F2CTSL | |
| SCHEMBL8569421 | 0.85 | ALDH1A1 (0.65) | TACR1CTSKHDAC8F2ALDH1A1 | |
| SCHEMBL7044299 | 0.85 | ATM (0.67) | CTSKHDAC8F2ALDH1A1CTSL | |
| SCHEMBL9716778 | 0.85 | ATM (0.67) | CTSKHDAC8F2ALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |