Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 18/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 16/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 15/20 | 0.65 |
| ▸ | HRH1 | P35367 | 4/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.60 |
| ▸ | CCR2 | P41597 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962799 | 1.00 | ADRA1A (0.65) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7962803 | 1.00 | ADRA1A (0.65) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| Hydrochloric Acid SCHEMBL7963307 | 0.99 | ADRA1A (0.64) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7963932 | 0.89 | ADRA1A (0.53) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| Hydrochloric Acid SCHEMBL7960516 | 0.88 | ADRA1A (0.53) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7966296 | 0.88 | ADRA1A (0.65) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7966301 | 0.88 | ADRA1A (0.65) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7970988 | 0.88 | ADRA1A (0.65) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| Hydrochloric Acid SCHEMBL7961383 | 0.87 | ADRA1A (0.64) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7963294 | 0.87 | ADRA1A (0.67) | ADRA1AADRA1BADRA1DHRH1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326372-B1 | BENIGN PROSTATE HYPERPLASIA | MERCK & CO., INC. | 2001-12-04 | — | — | US | claimed |
| US-6326372-B1 | BENIGN PROSTATE HYPERPLASIA | MERCK & CO., INC. | 2001-12-04 | — | — | US | disclosed |