Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5171415 | 0.70 | MCOLN3 (0.52) | MCOLN3TSHRLMNASMN1; SMN2PKM | |
| SCHEMBL3169939 | 0.70 | MCOLN3 (0.97) | MCOLN3TSHRLMNASMN1; SMN2PKM | |
| SCHEMBL18134604 | 0.69 | MCOLN3 (0.83) | MCOLN3TSHRLMNASMN1; SMN2PKM | |
| SCHEMBL3814970 | 0.68 | MCOLN3 (1.00) | MCOLN3TSHRLMNASMN1; SMN2PKM | |
| SCHEMBL30821997 | 0.68 | MCOLN3 (1.00) | MCOLN3TSHRLMNASMN1; SMN2PKM | |
| SCHEMBL21540450 | 0.67 | MAPT (0.53) | TSHRLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL15014129 | 0.66 | PKM (0.89) | MCOLN3TSHRLMNASMN1; SMN2PKM | |
| SCHEMBL12939718 | 0.66 | KDM4E (0.67) | MCOLN3TSHRLMNASMN1; SMN2PKM | |
| SCHEMBL12621872 | 0.66 | MCOLN3 (0.57) | MCOLN3TSHRLMNASMN1; SMN2PKM | |
| SCHEMBL10870104 | 0.66 | MCOLN3 (0.54) | MCOLN3TSHRLMNASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291511-B1 | Biarylalkanoic acids as cell adhesion inhibitors | MERCK & CO., INC. | 2001-09-18 | — | — | US | disclosed |