Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968575 | 0.93 | OPRD1 (0.50) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7967506 | 0.81 | OPRD1 (0.65) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7967503 | 0.81 | OPRD1 (0.65) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7971537 | 0.81 | OPRD1 (0.55) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7970789 | 0.80 | OPRD1 (0.56) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7971541 | 0.80 | OPRD1 (0.55) | OPRD1 | |
| SCHEMBL7973899 | 0.77 | OPRD1 (0.61) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7973900 | 0.77 | OPRD1 (0.61) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7970880 | 0.76 | OPRD1 (0.59) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7970878 | 0.76 | OPRD1 (0.59) | OPRD1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200978-B1 | FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS | PFIZER INC. | 2001-03-13 | — | — | US | disclosed |