Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971753 | 0.83 | HTT (0.36) | HTTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL7973654 | 0.83 | KDM4E (0.32) | CYP1A1CYP1A2CYP1B1HTTSMN1; SMN2 | |
| SCHEMBL7976556 | 0.81 | FFAR1 (0.33) | CYP1A1CYP1A2CYP1B1HTTSMN1; SMN2 | |
| SCHEMBL7976608 | 0.81 | KDM4E (0.30) | HTTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL30284250 | 0.77 | SIRT2 (0.38) | HTTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL4253743 | 0.77 | APP (0.37) | CYP1A2HTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7263829 | 0.77 | SIRT2 (0.38) | HTTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL5264237 | 0.76 | CYP1A2 (0.41) | CYP1A2HTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL361847 | 0.76 | KDM4E (0.50) | CYP1A2CYP1B1HTTSMN1; SMN2KDM4E | |
| SCHEMBL30284405 | 0.76 | KDM4E (0.50) | CYP1A2CYP1B1HTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281366-B1 | RADIATION TRANSPARENT ARTICLES | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-08-28 | — | — | US | disclosed |