SCHEMBL361847

SCHEMBL361847

C1=CC(c2ccccc2)(c2ccccc2)Oc2ccc3ccccc3c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.50
ALDH1A1 P00352 4/20 0.50
HPGD P15428 3/20 0.50
GLA P06280 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPT P10636 2/20 0.50
NPC1 O15118 1/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
HTT P42858 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
HSD17B10 Q99714 4/20 0.34
TSHR P16473 2/20 0.34
CYP2A6 P11509 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALOX15 P16050 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30284405 1.00 KDM4E (0.50) KDM4EALDH1A1HPGDGLAMEN1
SCHEMBL2517095 0.93 KDM4E (0.45) KDM4EALDH1A1HPGDGLAMEN1
SCHEMBL9056690 0.92 KDM4E (0.44) KDM4EALDH1A1HPGDGLAMEN1
SCHEMBL5615529 0.88 ALDH1A1 (0.42) KDM4EALDH1A1HPGDGLAMEN1
SCHEMBL5615321 0.88 SMN1; SMN2 (0.43) KDM4EALDH1A1HPGDGLAMEN1
SCHEMBL8921625 0.87 KDM4E (0.43) KDM4EALDH1A1HPGDGLAMEN1
SCHEMBL1387642 0.86 ALDH1A1 (0.40) KDM4EALDH1A1HPGDGLAMEN1
Paraquat SCHEMBL15014245 0.86 HTT (0.42) KDM4EALDH1A1HPGDGLAMEN1
SCHEMBL9104399 0.85 KDM4E (0.40) KDM4EALDH1A1HPGDGLAMEN1
SCHEMBL5094572 0.85 KDM4E (0.40) KDM4EALDH1A1HPGDGLAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117257652-A Photochromic orthodontic bracket adhesive and preparation method and application thereof 武汉大学 2023-12-22 CN claimed
CN-117165640-A In-situ microbial fermentation modified photochromic bacterial cellulose membrane and preparation method and application thereof 武汉纺织大学 2023-12-05 CN claimed
CN-111335051-A Environment-friendly leather-like velvet photosensitive and photochromic printing paste and preparation method thereof 广州明诺新材料科技有限公司 2020-06-26 CN claimed
US-10583666-B2 Ink composition DOMINO UK LIMITED (GB) 2020-03-10 US claimed
US-20170260412-A1 INK COMPOSITION DOMINO UK LIMITED (GB) 2017-09-14 US claimed
CN-104345968-A Touch sensor SAMSUNG ELECTRO MECH 2015-02-11 CN claimed
US-20070159594-A9 Photochromic blue light filtering materials and ophthalmic devices BAUSCH & LOMB INCORPORATED 2007-07-12 US claimed
US-20050254003-A1 Photochromic blue light filtering materials and ophthalmic devices BAUSCH & LOMB INCORPORATED 2005-11-17 US claimed
WO-2005000425-A1 PHOTOCHROMISM GOLF BALL FANTOM CO., LTD. (KR) 2005-01-06 WO claimed
US-20040266553-A1 Photochromic golf ball QINGDAO SM PARKER GOLF CO, LTD. (CN) 2004-12-30 US claimed
EP-0945451-B1 Photochrome diaryl-naphtopyran with at least one aminosubstituted aryl rest RODENSTOCK OPTIK G (DE) 2002-12-18 EP claimed
EP-1042311-A1 PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO 2,1-b]PYRANS TRANSITIONS OPTICAL, INC. (US) 2000-10-11 EP claimed
EP-0945451-A1 Photochrome diaryl-naphtopyran with at least one aminosubstituted aryl rest Optische Werke G. Rodenstock (DE) 1999-09-29 EP claimed
WO-1999031082-A1 PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO[2,1-b]PYRANS TRANSITIONS OPTICAL, INC. (US) 1999-06-24 WO claimed
CN-120061008-A Colorful color-changing spandex fiber and preparation method thereof 华峰化学股份有限公司 2025-05-30 CN disclosed
US-12247169-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2025-03-11 US disclosed
CN-119307251-A Environmental stimulus response type full-color spectrum color-changing microcapsule and preparation method and application thereof 江南大学 2025-01-14 CN disclosed
WO-1992009593-A1 PHOTOCHROMIC NAPHTHOPYRANS PPG INDUSTRIES, INC. (US) 1992-06-11 WO disclosed
CN-1061252-A Colouring method and product dyed thereby MATSUI SHIKISO KAGAKU KOGYOSHO (JP) 1992-05-20 CN disclosed
US-5066818-A Lenses, plastic transparencies PPG INDUSTRIES, INC. (US) 1991-11-19 US disclosed