Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7599418 | 0.99 | SMN1; SMN2 (0.43) | MAPTBCHEACHESMN1; SMN2PRKCI | |
| SCHEMBL7598124 | 0.89 | SMN1; SMN2 (0.48) | MAPTACHESMN1; SMN2PRKCIALDH1A1 | |
| Hydrochloric Acid SCHEMBL7598139 | 0.80 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7960394 | 0.77 | CHRM2 (0.45) | MAPTBCHEACHEPRKCIALDH1A1 | |
| Hydrochloric Acid SCHEMBL7597748 | 0.76 | CHRM2 (0.44) | MAPTBCHEACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL7602000 | 0.76 | TSHR (0.50) | MAPTBCHESMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6604506 | 0.75 | GAA (0.43) | MAPTBCHEGAAKDM4E | |
| SCHEMBL14568586 | 0.75 | PRKCI (0.62) | MAPTBCHEACHEPRKCIALDH1A1 | |
| SCHEMBL10490485 | 0.74 | GAA (0.42) | MAPTACHEALDH1A1GAATHRB | |
| SCHEMBL28324628 | 0.74 | GAA (0.50) | MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |