Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377173 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HSD17B10MAPTATMPOLB | |
| SCHEMBL5038420 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HSD17B10MAPTATMPOLB | |
| SCHEMBL3547447 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HSD17B10MAPTATMPOLB | |
| SCHEMBL13335420 | 0.73 | MAPT (1.00) | ALDH1A1HSD17B10MAPTPOLBGAA | |
| SCHEMBL8436040 | 0.72 | GAA (0.74) | ALDH1A1HSD17B10POLBGAAHPGD | |
| SCHEMBL999575 | 0.71 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTPOLBGAA | |
| SCHEMBL18719836 | 0.70 | ATM (0.97) | ALDH1A1HSD17B10MAPTATMRAB9A | |
| SCHEMBL15362563 | 0.69 | ALDH1A1 (0.68) | ALDH1A1MAPTGAARAB9ALMNA | |
| SCHEMBL4678070 | 0.69 | ALDH1A1 (0.74) | ALDH1A1HSD17B10MAPTATMPOLB | |
| SCHEMBL14582756 | 0.68 | GAA (0.62) | ALDH1A1HSD17B10POLBGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014310-A1 | PLEUROMUTILIN β-KETOESTERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | claimed |