Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2377229 | 0.86 | RORC (0.36) | RORC | |
| SCHEMBL2377231 | 0.86 | RORC (0.36) | RORC | |
| SCHEMBL1821899 | 0.74 | BACE1 (0.43) | — | |
| SCHEMBL1821897 | 0.74 | BACE1 (0.43) | — | |
| SCHEMBL7958112 | 0.70 | BACE1 (0.34) | — | |
| SCHEMBL7970180 | 0.70 | BACE1 (0.34) | — | |
| SCHEMBL1824141 | 0.66 | BACE1 (0.41) | — | |
| SCHEMBL2377313 | 0.66 | BACE1 (0.41) | — | |
| SCHEMBL7959952 | 0.65 | KDM4E (0.33) | — | |
| SCHEMBL1824011 | 0.63 | BACE1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |