Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 7/20 | 0.60 |
| ▸ | NOS1 | P29475 | 6/20 | 0.51 |
| ▸ | NOS3 | P29474 | 5/20 | 0.51 |
| ▸ | NOS2 | P35228 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7599927 | 0.99 | QRFPR (0.59) | QRFPRNOS1NOS3NOS2 | |
| SCHEMBL7598617 | 0.90 | QRFPR (0.58) | QRFPRNOS1NOS3NOS2 | |
| SCHEMBL7600919 | 0.82 | NOS1 (0.54) | QRFPRNOS1NOS3NOS2 | |
| SCHEMBL7973642 | 0.81 | QRFPR (0.67) | QRFPRNOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL7562296 | 0.81 | QRFPR (0.66) | QRFPRNOS1NOS3 | |
| SCHEMBL7598801 | 0.80 | NOS1 (0.49) | QRFPRNOS1NOS3NOS2 | |
| SCHEMBL7600307 | 0.80 | NOS1 (0.49) | QRFPRNOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL7563164 | 0.74 | QRFPR (0.67) | QRFPRNOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL7690698 | 0.74 | QRFPR (0.51) | QRFPRNOS1NOS3NOS2 | |
| SCHEMBL7568588 | 0.74 | QRFPR (0.69) | QRFPRNOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |