Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968258 | 0.85 | ALDH1A1 (0.35) | ALDH1A1LMNAKDM4EMAPK1TYMS | |
| SCHEMBL6929228 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL6931344 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL6931667 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL7567255 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL7564062 | 0.71 | KDM4E (0.55) | ALDH1A1LMNAKDM4EMAPK1KMT2A | |
| SCHEMBL3363408 | 0.71 | KDM4E (0.55) | ALDH1A1LMNAKDM4EMAPK1KMT2A | |
| SCHEMBL7565537 | 0.71 | KDM4E (0.55) | ALDH1A1LMNAKDM4EMAPK1KMT2A | |
| SCHEMBL6929995 | 0.70 | SRD5A2 (0.43) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL30901483 | 0.70 | CYP2A6 (0.52) | ALDH1A1LMNACYP2A6CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |