Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968349 | 0.65 | TP53 (0.34) | ALDH1A1 | |
| SCHEMBL7964673 | 0.65 | — | — | |
| SCHEMBL7632455 | 0.62 | DYRK1A (0.39) | CHEK1LIMK1DYRK1ACLK4KDM4E | |
| SCHEMBL8053102 | 0.61 | HSD17B10 (0.46) | ALDH1A1HPGDTSHRPKMHSD17B10 | |
| SCHEMBL8041231 | 0.57 | LMNA (0.33) | CHEK1LIMK1DYRK1ACLK4KDM4E | |
| SCHEMBL5632849 | 0.57 | MEN1 (0.55) | ALDH1A1HPGD | |
| SCHEMBL8054632 | 0.57 | KDM4E (0.35) | CHEK1LIMK1DYRK1ACLK4KDM4E | |
| SCHEMBL7964619 | 0.57 | — | — | |
| SCHEMBL5630873 | 0.53 | L3MBTL1 (0.65) | ALDH1A1TSHR | |
| SCHEMBL5656919 | 0.53 | SMN1; SMN2 (0.58) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242437-B1 | HAS HIGHER ANTIMICROBIAL ACTIVITY AGAINST METHICILLINE-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA), PENICILLIN-RESISTANT STREPTOCOCCUS PNEUMONIAE (PRSP), AND IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA ONIUM SALT | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0947517-A1 | CEPHEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |