Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755422 | 0.87 | CYP17A1 (0.54) | CYP17A1PPARGPPARADRD2LMNA | |
| SCHEMBL15709727 | 0.86 | LMNA (0.62) | CYP17A1CYP4Z1PPARGPPARALMNA | |
| SCHEMBL7421780 | 0.85 | MAPT (0.47) | CYP4F2CYP4A11LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4495406 | 0.84 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1MAPTSMN1; SMN2 | |
| SCHEMBL6376720 | 0.84 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1MAPTSMN1; SMN2 | |
| SCHEMBL1000732 | 0.83 | NR1H4 (0.58) | CYP17A1PPARGPPARADRD2PTGDR2 | |
| SCHEMBL12677009 | 0.83 | CYP17A1 (0.58) | CYP17A1PPARGPPARADRD2PTGDR2 | |
| SCHEMBL3173008 | 0.83 | PPARG (0.53) | CYP17A1PPARGPPARADRD2LMNA | |
| SCHEMBL23513700 | 0.82 | CA12 (0.46) | CYP4F2CYP4A11CYP17A1PPARGLMNA | |
| SCHEMBL6984766 | 0.81 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP4Z1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1223659-A | Fused imidazopyridine derivatives as antihyperlipidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-21 | — | — | CN | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |