Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.49 |
| ▸ | CCR5 | P51681 | 15/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | INSR | P06213 | 2/20 | 0.38 |
| ▸ | NPM1 | P06748 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972201 | 0.93 | CCR2 (0.59) | CCR2CCR5 | |
| SCHEMBL7972715 | 0.89 | CCR2 (0.48) | CCR2CCR5 | |
| SCHEMBL7969928 | 0.89 | CCR2 (0.59) | CCR2CCR5 | |
| SCHEMBL7975445 | 0.88 | CCR2 (0.52) | CCR2CCR5 | |
| SCHEMBL7928486 | 0.87 | CCR2 (0.60) | CCR2CCR5 | |
| SCHEMBL7968766 | 0.86 | CCR2 (0.51) | CCR2CCR5 | |
| SCHEMBL7975020 | 0.85 | CCR2 (0.49) | CCR2CCR5 | |
| SCHEMBL7929528 | 0.83 | CCR2 (0.60) | CCR2CCR5 | |
| SCHEMBL7972105 | 0.82 | CCR2 (0.62) | CCR2CCR5 | |
| SCHEMBL7958790 | 0.82 | CCR2 (0.64) | CCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |