Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 8/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.40 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.37 |
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16160236 | 0.85 | FNTA (0.35) | ITGA4ITGB1FNTAFNTBCYP11B1 | |
| SCHEMBL17145867 | 0.83 | FNTA (0.35) | ITGA4ITGB1FNTAFNTBCYP11B1 | |
| SCHEMBL7971638 | 0.83 | FNTA (0.47) | FNTAFNTBCYP11B1CYP11B2MAPT | |
| SCHEMBL7971101 | 0.82 | FNTA (0.48) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL7972160 | 0.77 | ITGA4 (0.38) | ITGA4ITGB1ITGB7GPR132ALDH1A1 | |
| SCHEMBL7968423 | 0.77 | FNTA (0.49) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL8141634 | 0.75 | FNTA (0.39) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL8141630 | 0.75 | FNTA (0.39) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL7968966 | 0.72 | FNTA (0.44) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL16160199 | 0.71 | FNTA (0.41) | FNTAFNTBCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |