Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561685 | 1.00 | LMNA (0.45) | LMNATHRBATML3MBTL1EPHX1 | |
| SCHEMBL1242806 | 0.98 | LMNA (0.43) | LMNATHRBATML3MBTL1EPHX1 | |
| SCHEMBL1242807 | 0.98 | LMNA (0.43) | LMNATHRBATML3MBTL1EPHX1 | |
| SCHEMBL2082055 | 0.92 | NPSR1 (0.44) | LMNATHRBATML3MBTL1EPHX1 | |
| SCHEMBL2082056 | 0.92 | NPSR1 (0.44) | LMNATHRBATML3MBTL1EPHX1 | |
| SCHEMBL4381636 | 0.83 | NPSR1 (0.49) | EPHX1NPSR1ALDH1A1HTTKDM4E | |
| SCHEMBL4381639 | 0.83 | NPSR1 (0.49) | EPHX1NPSR1ALDH1A1HTTKDM4E | |
| SCHEMBL8976976 | 0.81 | NPSR1 (0.46) | LMNATHRBATML3MBTL1EPHX1 | |
| SCHEMBL8977045 | 0.81 | NPSR1 (0.46) | LMNATHRBATML3MBTL1EPHX1 | |
| SCHEMBL10560406 | 0.81 | NPSR1 (0.46) | EPHX1NPSR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281295-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2001-08-28 | — | — | US | disclosed |
| EP-0735083-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL EUROP (CH) | 2000-02-09 | — | — | EP | disclosed |
| EP-0735083-A1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1996-10-02 | — | — | EP | disclosed |
| US-RE32975-E | FUNGICIDES, BACTERICIDES, FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| US-4284629-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |