Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taurine SCHEMBL28005328 | 0.87 | LMNA (0.70) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL28148201 | 0.86 | — | — | |
| Taurine SCHEMBL29931159 | 0.86 | — | — | |
| Taurine SCHEMBL42632 | 0.86 | BLM (1.00) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL30191395 | 0.86 | — | — | |
| Taurine SCHEMBL30179154 | 0.86 | — | — | |
| Taurine SCHEMBL23068 | 0.86 | — | — | |
| Taurine SCHEMBL9069180 | 0.85 | LMNA (0.67) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL27277439 | 0.83 | — | — | |
| Taurine SCHEMBL11026626 | 0.83 | LMNA (0.82) | LMNASLC6A6CYP2C19BLMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268345-B1 | BPI-RELATED POLYPEPTIDES WITH LIPIDS AND, PARTICULARLY, LIPID CARRIER SUBSTANCES SUCH AS PHOSPHOLIPIDS, LIPOSOMES AND NONIONIC DETERGENTS AS WELL AS COMPOSITIONS WITH POLOXAMER SURFACTANTS. | XOMA CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-6057293-A | BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN OR A BIOLOGICALLY ACTIVE FRAGMENT, ANALOG OR VARIANT, AND A NONIONIC DETERGENT LIPID CARRIER TO SOLUBILIZE THE PROTEIN OR FRAGMENT OR ANALOG OR VARIANT | XOMA CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| US-5932544-A | MIXTURE WITH LIPID CARRIER | XOMA CORPORATION (US) | 1999-08-03 | — | — | US | disclosed |