Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 6/20 | 0.40 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7967237 | 0.99 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| SCHEMBL7975518 | 0.89 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7MEN1 | |
| Hydrochloric Acid SCHEMBL7964569 | 0.89 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7MEN1 | |
| SCHEMBL7966199 | 0.88 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| Hydrochloric Acid SCHEMBL7954290 | 0.88 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| SCHEMBL7419797 | 0.88 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BMAP3K7ABCB1 | |
| SCHEMBL7338979 | 0.88 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| Hydrochloric Acid SCHEMBL7963578 | 0.88 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| Hydrochloric Acid SCHEMBL7962173 | 0.87 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7ABCB1 | |
| SCHEMBL7339127 | 0.87 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1BMAP3K7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |