SCHEMBL797237

SCHEMBL797237

Cc1c2cc3ccccc3cc2cc2cc3ccccc3cc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.46
CYP2A6 P11509 7/20 0.46
TDP1 Q9NUW8 2/20 0.46
HSD17B10 Q99714 4/20 0.43
HPGD P15428 4/20 0.43
HIF1A Q16665 3/20 0.43
TSHR P16473 2/20 0.43
RAB9A P51151 2/20 0.43
CYP3A4 P08684 2/20 0.43
CASP1 P29466 2/20 0.43
CASP7 P55210 2/20 0.43
MAPK1 P28482 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP1A2 P05177 5/20 0.42
MAPT P10636 3/20 0.42
ALDH1A1 P00352 7/20 0.42
CYP1B1 Q16678 1/20 0.42
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6891640 0.93 CYP1A2 (0.48) NQO1CYP2A6TDP1HSD17B10HPGD
SCHEMBL29853846 0.88 CYP2A6 (0.50) NQO1CYP2A6TDP1HSD17B10HPGD
SCHEMBL4642683 0.88 CYP2A6 (0.50) NQO1CYP2A6TDP1HSD17B10HPGD
SCHEMBL1538428 0.85 CYP1A2 (0.41) NQO1CYP2A6TDP1HSD17B10HPGD
SCHEMBL29512148 0.85 CYP1A2 (0.41) NQO1CYP2A6TDP1HSD17B10HPGD
SCHEMBL29853748 0.85 CYP1A2 (0.58) NQO1CYP2A6TDP1HSD17B10HPGD
SCHEMBL28999606 0.85 CYP1A2 (0.58) NQO1CYP2A6TDP1HSD17B10HPGD
SCHEMBL4646013 0.84 HSD17B10 (0.50) NQO1CYP2A6TDP1HSD17B10HPGD
SCHEMBL7501835 0.83 NQO1 (0.46) NQO1CYP2A6TDP1HSD17B10HPGD
SCHEMBL687284 0.83 NQO1 (0.46) NQO1CYP2A6TDP1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1262469-B1 POLYACENE DERIVATIVES AND PRODUCTION THEREOF JAPAN SCIENCE & TECH AGENCY (JP) 2012-01-11 EP disclosed