SCHEMBL4646013

SCHEMBL4646013

Cc1c2ccccc2c(C)c2cc3cc4cc5ccccc5cc4cc3cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.50
HIF1A Q16665 3/20 0.50
TSHR P16473 3/20 0.50
HPGD P15428 3/20 0.50
CYP3A4 P08684 2/20 0.50
CASP1 P29466 2/20 0.50
CASP7 P55210 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
RAB9A P51151 2/20 0.50
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.50
CYP2A6 P11509 6/20 0.44
CYP1A2 P05177 5/20 0.44
ALDH1A1 P00352 7/20 0.44
CYP1B1 Q16678 1/20 0.44
NQO1 P15559 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
ALOX15 P16050 1/20 0.41
HBB P68871 1/20 0.41
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29853851 0.95 HSD17B10 (0.54) HSD17B10HIF1ATSHRHPGDCYP3A4
SCHEMBL4644690 0.95 HSD17B10 (0.54) HSD17B10HIF1ATSHRHPGDCYP3A4
SCHEMBL687284 0.90 NQO1 (0.46) HSD17B10HIF1ATSHRHPGDCYP3A4
SCHEMBL7501835 0.90 NQO1 (0.46) HSD17B10HIF1ATSHRHPGDCYP3A4
SCHEMBL4642683 0.89 CYP2A6 (0.50) HSD17B10HIF1ATSHRHPGDCYP3A4
SCHEMBL29853846 0.89 CYP2A6 (0.50) HSD17B10HIF1ATSHRHPGDCYP3A4
SCHEMBL4648094 0.89 ALDH1A1 (0.57) HSD17B10HIF1ATSHRHPGDCYP3A4
SCHEMBL164133 0.85 HSD17B10 (0.45) HSD17B10HIF1ATSHRHPGDCYP3A4
SCHEMBL797237 0.84 NQO1 (0.46) HSD17B10HIF1ATSHRHPGDCYP3A4
SCHEMBL1976533 0.84 CYP2A6 (0.50) HSD17B10HIF1ATSHRHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
US-11857385-B2 Method of producing plate denture, curable composition for stereolithography, and plate denture production kit TOKUYAMA DENTAL CORPORATION (JP) 2024-01-02 US disclosed
US-20230137898-A1 METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT TOKUYAMA DENTAL CORPORATION (JP) 2023-05-04 US disclosed
EP-4091578-A1 METHOD FOR PRODUCING PLATE DENTURE, CURABLE STEREOLITHOGRAPHIC COMPOSITION, AND PLATE DENTURE PRODUCTION KIT Tokuyama Dental Corporation (JP) 2022-11-23 EP disclosed
CN-103988313-A Method for manufacturing silicon substrate having textured structure TOKUYAMA CORPROATION 2014-08-13 CN disclosed
EP-1591098-B1 Cationically curable composition for dental use TOKUYAMA CORP (JP) 2008-08-13 EP disclosed
US-7365106-B2 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2008-04-29 US disclosed
EP-1431315-B1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORP (JP) 2007-10-17 EP disclosed
CN-1732883-A Cationically curable composition for dental use TOKUYAMA CORP (JP) 2006-02-15 CN disclosed
US-20050250868-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-10 US disclosed
EP-1591098-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-02 EP disclosed
US-20040186195-A1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORPORATION (JP) 2004-09-23 US disclosed
CN-1513884-A Photopolymerization initiator and composition capable of photopolymerization 株式会社德山 2004-07-21 CN disclosed
EP-1431315-A2 Photopolymerization initiator and photopolymerizable composition Tokuyama Corporation (JP) 2004-06-23 EP disclosed