Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989727 | 0.96 | CYP19A1 (0.55) | CYP19A1PGRLMNATSHRHTT | |
| SCHEMBL7973407 | 0.96 | CYP19A1 (0.55) | CYP19A1PGRLMNATSHRHTT | |
| SCHEMBL7982844 | 0.95 | CYP19A1 (0.53) | CYP19A1PGRLMNATSHRHTT | |
| SCHEMBL7972170 | 0.95 | CYP19A1 (0.53) | CYP19A1PGRLMNATSHRHTT | |
| SCHEMBL7596818 | 0.86 | CYP19A1 (0.57) | CYP19A1PGRHTTNAMPTNR3C2 | |
| SCHEMBL7972622 | 0.85 | CYP19A1 (0.56) | CYP19A1PGRRAB9ANAMPTMAPT | |
| SCHEMBL4019035 | 0.85 | CYP19A1 (0.65) | CYP19A1PGRLMNAHTTSMN1; SMN2 | |
| SCHEMBL7983897 | 0.84 | CYP19A1 (0.80) | CYP19A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL7986035 | 0.80 | CYP19A1 (0.78) | CYP19A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL7983776 | 0.80 | CYP19A1 (0.78) | CYP19A1LMNATSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |