Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982844 | 0.91 | CYP19A1 (0.53) | CYP19A1PGRNAMPTHRH2HRH1 | |
| SCHEMBL7972170 | 0.91 | CYP19A1 (0.53) | CYP19A1PGRNAMPTHRH2HRH1 | |
| SCHEMBL7983044 | 0.89 | CYP19A1 (0.72) | CYP19A1NAMPT | |
| SCHEMBL7989727 | 0.89 | CYP19A1 (0.55) | CYP19A1PGRNAMPTHRH2HRH1 | |
| SCHEMBL7973407 | 0.87 | CYP19A1 (0.55) | CYP19A1PGRNAMPTHRH2HRH1 | |
| SCHEMBL7972389 | 0.85 | CYP19A1 (0.56) | CYP19A1PGRNAMPTHRH2HRH1 | |
| SCHEMBL4019035 | 0.81 | CYP19A1 (0.65) | CYP19A1PGRNAMPTRAB9A | |
| SCHEMBL7538755 | 0.77 | PRSS1 (0.59) | RAB9A | |
| SCHEMBL7596818 | 0.77 | CYP19A1 (0.57) | CYP19A1PGRNAMPTMAPT | |
| SCHEMBL7473770 | 0.75 | MAOB (0.57) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |