Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7974149 | 0.97 | EGFR (0.43) | EGFRBRD4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7972454 | 0.85 | EGFR (0.46) | EGFRBRD4ALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7974150 | 0.83 | BRD4 (0.45) | EGFRBRD4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7960599 | 0.82 | PDCD1LG2 (0.37) | BRD4ALDH1A1L3MBTL1POLBTHRB | |
| Hydrochloric Acid SCHEMBL7972228 | 0.81 | PDCD1LG2 (0.36) | BRD4ALDH1A1L3MBTL1POLBTHRB | |
| SCHEMBL2473897 | 0.77 | EGFR (0.51) | EGFRBRD4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30027960 | 0.77 | EGFR (0.54) | EGFRBRD4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5433157 | 0.77 | BRD4 (0.53) | EGFRBRD4ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5426752 | 0.76 | ALDH1A1 (0.53) | EGFRBRD4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL609574 | 0.75 | EGFR (0.52) | EGFRBRD4ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |