Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 5/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6106318 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH | |
| SCHEMBL7836904 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH | |
| SCHEMBL7836897 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH | |
| SCHEMBL12303492 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH | |
| SCHEMBL6106312 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH | |
| SCHEMBL23951605 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH | |
| SCHEMBL7494189 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH | |
| SCHEMBL8094092 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH | |
| SCHEMBL6105682 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH | |
| SCHEMBL31177953 | 1.00 | RORC (0.47) | RORCDRD2DRD3MC4RFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |