Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972689 | 1.00 | DRD2 (0.41) | DRD2OPRM1MEN1LMNAADRB2 | |
| SCHEMBL651919 | 0.93 | DRD2 (0.39) | DRD2OPRM1MEN1LMNAADRB2 | |
| SCHEMBL651917 | 0.93 | DRD2 (0.39) | DRD2OPRM1MEN1LMNAADRB2 | |
| SCHEMBL652740 | 0.90 | CCR1 (0.40) | DRD2OPRM1CCR1OPRL1 | |
| SCHEMBL652742 | 0.90 | CCR1 (0.40) | DRD2OPRM1CCR1OPRL1 | |
| SCHEMBL655191 | 0.89 | DRD2 (0.38) | DRD2OPRM1MEN1LMNAADRB2 | |
| SCHEMBL655189 | 0.89 | DRD2 (0.38) | DRD2OPRM1MEN1LMNAADRB2 | |
| SCHEMBL7976315 | 0.89 | CCR1 (0.38) | DRD2SLC6A4HTR2BHTR1ADRD1 | |
| SCHEMBL7976310 | 0.89 | CCR1 (0.38) | DRD2SLC6A4HTR2BHTR1ADRD1 | |
| SCHEMBL654334 | 0.87 | DRD2 (0.38) | DRD2OPRM1MEN1LMNAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329385-B1 | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, VIRAL DISEASES AND GASTROINTESTINAL DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |