Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970292 | 0.88 | HDAC8 (0.32) | P2RX7HDAC8HDAC6 | |
| SCHEMBL4058384 | 0.83 | KDM4E (0.32) | BUB1 | |
| SCHEMBL4058383 | 0.83 | KDM4E (0.32) | BUB1 | |
| SCHEMBL4392500 | 0.82 | KDM1A (0.41) | MEN1KMT2ARAB9ANPC1P2RX7 | |
| SCHEMBL4392496 | 0.82 | KDM1A (0.41) | MEN1KMT2ARAB9ANPC1P2RX7 | |
| Hydrochloric Acid SCHEMBL7906091 | 0.81 | KDM1A (0.40) | MEN1KMT2ARAB9ANPC1P2RX7 | |
| SCHEMBL4245801 | 0.76 | — | — | |
| SCHEMBL4245803 | 0.76 | — | — | |
| SCHEMBL7761724 | 0.75 | PSEN1 (0.35) | — | |
| SCHEMBL7760822 | 0.74 | MMP2 (0.40) | MEN1KMT2AGAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005767-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2001-01-25 | — | — | WO | claimed |