Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | FASN | P49327 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185373 | 0.93 | CYP2D6 (0.62) | SLC6A7MEN1KMT2AHSD11B1CYP2D6 | |
| SCHEMBL7975189 | 0.88 | CYP2D6 (0.62) | SLC6A7MEN1KMT2AHSD11B1CYP2D6 | |
| SCHEMBL7958924 | 0.86 | S1PR2 (0.55) | SLC6A7MEN1KMT2AHSD11B1CYP2D6 | |
| SCHEMBL7970388 | 0.85 | CYP2D6 (0.62) | SLC6A7MEN1KMT2AHSD11B1CYP2D6 | |
| SCHEMBL7970184 | 0.84 | CYP2D6 (0.61) | HSD11B1CYP2D6POLBALDH1A1CA12 | |
| SCHEMBL14817973 | 0.84 | CYP2D6 (0.65) | KMT2AHSD11B1CYP2D6HPGDPOLB | |
| SCHEMBL9192739 | 0.82 | TSHR (0.58) | MEN1KMT2ACYP2D6HPGDMAPK1 | |
| SCHEMBL7969951 | 0.82 | CYP2D6 (0.62) | MEN1KMT2AHSD11B1CYP2D6HPGD | |
| SCHEMBL1221347 | 0.81 | KMT2A (0.62) | SLC6A7MEN1KMT2AHSD11B1HPGD | |
| SCHEMBL7975184 | 0.81 | HTT (0.54) | SLC6A7MEN1KMT2ACYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291464-B1 | POTENTIATION OF THE CHOLINERGIC ACTIVITY; THERAPEUTIC TREATMENT OF AMNESIA, DEMENTIA OR SENILE DEMENTIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0968201-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998035951-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-20 | — | — | WO | disclosed |