Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975189 | 0.89 | CYP2D6 (0.62) | CYP2D6CA12CA1CA2CA7 | |
| SCHEMBL9185373 | 0.89 | CYP2D6 (0.62) | CYP2D6CA12CA1CA2CA7 | |
| SCHEMBL7970184 | 0.87 | CYP2D6 (0.61) | CYP2D6CA12CA1CA2CA7 | |
| SCHEMBL14817973 | 0.87 | CYP2D6 (0.65) | CYP2D6CA12CA1CA2CA7 | |
| SCHEMBL7969951 | 0.85 | CYP2D6 (0.62) | CYP2D6CA12CA1CA2CA7 | |
| SCHEMBL7972787 | 0.85 | SLC6A7 (0.66) | CYP2D6CA12CA1CA2CA7 | |
| SCHEMBL7972620 | 0.84 | CYP2D6 (0.60) | CYP2D6CA12CA1CA2CA7 | |
| SCHEMBL7970528 | 0.84 | CYP2D6 (0.60) | CYP2D6CA12CA1CA2CA7 | |
| SCHEMBL7975141 | 0.84 | CYP2D6 (0.57) | CYP2D6CA12CA1CA2CA7 | |
| SCHEMBL7975191 | 0.84 | CYP2D6 (0.57) | CYP2D6CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291464-B1 | POTENTIATION OF THE CHOLINERGIC ACTIVITY; THERAPEUTIC TREATMENT OF AMNESIA, DEMENTIA OR SENILE DEMENTIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0968201-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998035951-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-20 | — | — | WO | disclosed |