Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 20/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699155 | 0.86 | CCR3 (0.63) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| Bromide SCHEMBL6217023 | 0.85 | CCR3 (0.62) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6780550 | 0.75 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6780545 | 0.75 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7656814 | 0.74 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL18840939 | 0.74 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7656820 | 0.74 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6215640 | 0.72 | CCR3 (1.00) | CCR3HTR2A | |
| SCHEMBL6337473 | 0.72 | CCR3 (0.43) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6337783 | 0.71 | CCR3 (1.00) | CCR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331541-B1 | TREATING ASTHMA, ALLERGIC RHINITIS, ATOPIC DERMATITIS AND INFLAMMATORY BOWEL DISEASES | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2001-12-18 | — | — | US | disclosed |