Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | F9 | P00740 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 5/20 | 0.35 |
| ▸ | PLAU | P00749 | 5/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 3/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140125 | 0.89 | MEN1 (0.39) | F10F9F11PLGPLAU | |
| SCHEMBL10140128 | 0.84 | F10 (0.34) | F10F9F11PLGPLAU | |
| SCHEMBL10140130 | 0.83 | HDAC3 (0.43) | CHEK2 | |
| SCHEMBL12758129 | 0.81 | MEN1 (0.36) | F10F9F11PLGPLAU | |
| SCHEMBL7960714 | 0.78 | CHEK2 (0.39) | CHEK2 | |
| SCHEMBL16258967 | 0.77 | MEN1 (0.39) | F10F9F11PLGPLAU | |
| SCHEMBL10140129 | 0.76 | HDAC1 (0.34) | CHEK2KLKB1 | |
| SCHEMBL10140006 | 0.74 | CHEK2 (0.38) | CHEK2 | |
| SCHEMBL10140040 | 0.73 | CHEK2 (0.34) | CHEK2 | |
| SCHEMBL10140004 | 0.71 | SCD (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |